fbpx
Wikipedia

In organic chemistry, tolyl groups are functional groups related to toluene. They have the general formulaCH3C6H4−R, the change of the relative position of the methyl and the R substituent on the aromatic ring can generate three possible structural isomers 1,2 (ortho), 1,3 (meta), and 1,4 (para). Tolyl groups are aryl groups which are commonly found in the structure of diverse chemical compounds. They are considered nonpolar and hydrophobic groups.

Structures of the three isomers of tolyl group

The functionalization to include tolyl groups into compounds is often done by Williamson etherification, using tolyl alcohols as reagents, or by C-C coupling reactions. Tolyl sulfonates are excellent leaving groups in nucleophilic substitutions, for this reason, they are commonly generated as intermediaries to activate alcohols. To this end, 4-toluenesulfonyl chloride is reacted in the presence of a base with the corresponding alcohol.

Tolyl groups Article Talk Language Watch Edit 160 160 Redirected from Tolyl In organic chemistry tolyl groups are functional groups related to toluene 1 They have the general formula CH3C6H4 R the change of the relative position of the methyl and the R substituent on the aromatic ring can generate three possible structural isomers 1 2 ortho 1 3 meta and 1 4 para Tolyl groups are aryl groups which are commonly found in the structure of diverse chemical compounds They are considered nonpolar and hydrophobic groups Structures of the three isomers of tolyl group The functionalization to include tolyl groups into compounds is often done by Williamson etherification using tolyl alcohols as reagents or by C C coupling reactions Tolyl sulfonates are excellent leaving groups in nucleophilic substitutions for this reason they are commonly generated as intermediaries to activate alcohols To this end 4 toluenesulfonyl chloride is reacted in the presence of a base with the corresponding alcohol References Edit Revised Nomenclature for Radicals Ions Radical Ions and Related Species IUPAC Recommendations 1993 Appendix Queen Mary University of London This organic chemistry article is a stub You can help Wikipedia by expanding it vte Retrieved from https en wikipedia org w index php title Tolyl groups amp oldid 1084331673, wikipedia, wiki, book,

books

, library,

article

, read, download, free, free download, mp3, video, mp4, 3gp, jpg, jpeg, gif, png, picture, music, song, movie, book, game, games.